A bad trip is an acute adverse psychological reaction to classic hallucinogens. With proper screening, preparation, and support in a regulated setting these are usually benign. A bad trip on psilocybin, for instance, often features intense anxiety, confusion, and agitation, or even psychotic episodes. As of 2011, exact data on the frequency of bad trips are not available.
Harm reduction, or harm minimization, refers to a range of intentional practices and public health policies designed to lessen the negative social and/or physical consequences associated with various human behaviors, both legal and illegal. Harm reduction is used to decrease negative consequences of recreational drug use and sexual activity without requiring abstinence, recognizing that those unable or unwilling to stop can still make positive change to protect themselves and others.
Naloxone, sold under the brand name Narcan among others, is a medication used to reverse or reduce the effects of opioids. It is used to counter decreased breathing in opioid overdose. Effects begin within two minutes when given intravenously, and within five minutes when injected into a muscle. The medicine can also be administered by spraying it into a person's nose. Naloxone blocks the effects of opioids for 30 to 90 minutes. Multiple doses may be required, as the duration of action of some opioids is greater than that of naloxone. Emergency medical services data from Massachusetts found that 93.5% of people given naloxone survived their overdose.
A needle and syringe programme (NSP), also known as needle exchange program (NEP), is a social service that allows injecting drug users (IDUs) to obtain clean and unused hypodermic needles and associated paraphernalia at little or no cost. It is based on the philosophy of harm reduction that attempts to reduce the risk factors for blood-borne diseases such as HIV/AIDS and hepatitis.
Primum non nocere is a Latin phrase that means "first, do no harm". The phrase is sometimes recorded as primum nil nocere.
Snus is a tobacco product, originating from a variant of dry snuff in early 18th-century Sweden. It is placed between the upper lip and gum for extended periods, as a form of sublabial administration. Snus is not fermented. Although used similarly to American dipping tobacco, snus does not typically result in the need for spitting and, unlike naswar, snus is steam-pasteurized.
A vaporizer or vaporiser, colloquially known as a vape, is a device used to vaporize substances for inhalation. Plant substances can be used, commonly cannabis, tobacco, or other herbs or blends of essential oil. However, they are most commonly filled with a combination propylene glycol, glycerin, and drugs such as nicotine or tetrahydrocannabinol as a liquid solution.
Set and setting, when referring to a psychedelic drug experience or the use of other psychoactive substances, means one's mindset and the physical and social environment in which the user has the experience. Set and setting are factors that can condition the effects of psychoactive substances: "Set" refers to the mental state a person brings to the experience, like thoughts, mood and expectations; "setting" to the physical and social environment. This is especially relevant for psychedelic experiences in either a therapeutic or recreational context.
This is a list of psychedelic literature, works related to psychedelic drugs and the psychedelic experience. Psychedelic literature has also been defined as textual works that arose from the proliferation of psychiatric and psychotherapeutic research with hallucinogens during the 1950s and early 1960s in North America and Europe.
Journal Citation Reports (JCR) is an annual publication by Clarivate. It has been integrated with the Web of Science and is accessed from the Web of Science Core Collection. It provides information about academic journals in the natural and social sciences, including impact factors. The JCR was originally published as a part of the Science Citation Index. Currently, the JCR, as a distinct service, is based on citations compiled from the Science Citation Index Expanded and the Social Sciences Citation Index. As of the 2023 edition, journals from the Arts and Humanities Citation Index and the Emerging Sources Citation Index will also be included.
Tobacco harm reduction (THR) is a public health strategy to lower the health risks to individuals and wider society associated with using tobacco products. It is an example of the concept of harm reduction, a strategy for dealing with the use of drugs. Tobacco smoking is widely acknowledged as a leading cause of illness and death, and reducing smoking is vital to public health.
DrugScience or Drug Science (originally called the Independent Scientific Committee on Drugs (ISCD)) is a UK-based drugs advisory committee proposed and initially funded by hedge fund manager Toby Jackson. It is chaired by Professor David Nutt and was officially launched on 15 January 2010 with the help of the Centre for Crime and Justice Studies. The primary aim of the committee is to review and investigate the scientific evidence of drug harms without the political interference that could result from government affiliation.
The Journal of Global Drug Policy and Practice describes itself as an open access peer-reviewed public health journal. Critics say it is biased, not peer reviewed, and not a legitimate scientific journal. It is funded by the US Department of Justice.
Drug cultures are examples of countercultures that are primarily defined by spiritual, medical, and recreational drug use. They may be focused on a single drug, or endorse polydrug use. They sometimes eagerly or reluctantly initiate newcomers, but their main functions are to share drug experiences, to reduce harm by providing knowledge of how to use drugs as safely as possible, and to exchange information on suppliers and avoidance of law enforcement.
The Three Rs (3Rs) are guiding principles for more ethical use of animals in product testing and scientific research. They were first described by W. M. S. Russell and R. L. Burch in 1959. The 3Rs are:
- Replacement:methods which avoid or replace the use of animals in research
- Reduction: use of methods that enable researchers to obtain comparable levels of information from fewer animals, or to obtain more information from the same number of animals.
- Refinement: use of methods that alleviate or minimize potential pain, suffering or distress, and enhance animal welfare for the animals used.
4-Methylbuphedrone, is a stimulant drug of the cathinone class that has been sold online as a designer drug.
ALTEX: Alternatives to Animal Experimentation is a quarterly peer-reviewed scientific journal covering alternatives to animal experimentation and related issues of bioethics, seeking to promote the replacement, reduction, and refinement of animal use in research. It was originally published in German and established in 1984 as ALTEX: Alternativen zu Tierexperimenten and is published by Springer Spektrum on behalf of the Swiss Society ALTEX Edition.
Riccardo Polosa is an Italian respiratory physician. According to a paper published in BMC Public Health, he is the most prolific author in the field of electronic cigarettes, as of 2014. "Full Professor of Internal Medicine and specialist of Respiratory Diseases and Clinical Immunology at the University of Catania as well as the Founder and Clinical Director of the Center for Tobacco Research and Scientific Director of the Center of Excellence for the acceleration of Harm Reduction (CoEHAR) at the same University." His research interests center on asthma, COPD, respiratory diseases, smoking-related diseases, smoking prevention and cessation, tobacco harm reduction, and new tobacco products. Since 2009, his research team has been involved in studies on the impact of e-cigarettes, and they were the first in the world to publish a randomized controlled trial on e-cigarettes.
Gerry Stimson is a British public health social scientist, emeritus professor at Imperial College London from 2004, and an honorary professor at the London School of Hygiene and Tropical Medicine from 2017. Stimson has over 220 scientific publications mainly on social and health aspects of illicit drug use, including HIV infection. He has sat on numerous editorial boards including AIDS, Addiction, and European Addiction Research, and with Tim Rhodes he was the co-editor-in-chief of the International Journal of Drug Policy from 2000 to 2016. He is one of the global leaders for research on and later advocacy for harm reduction.
Drug checking or pill testing is a way to reduce the harm from drug consumption by allowing users to find out the content and purity of substances that they intend to consume. This enables users to make safer choices: to avoid more dangerous substances, to use smaller quantities, and to avoid dangerous combinations.
