Prevention of viral hemorrhagic fever

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VHF isolation precautions poster VHFisolation.png
VHF isolation precautions poster

Prevention of viral hemorrhagic fever is similar for the different viruses. There are a number of different viral hemorrhagic fevers including Ebola virus disease, Lassa fever, Rift valley fever, Marburg virus disease, Crimean-Congo haemorrhagic fever (CCHF) and yellow fever. [1] Lassa, Ebola, Marburg and CCHF can be spread by direct contact with the body fluids of those infected. [1] Thus the content here covers the prevention of Ebola.

Contents

Standard precautions

An example of a handwashing station in a low resource setting Handwashingstation.jpg
An example of a handwashing station in a low resource setting

The use of standard precautions is recommended with all patients in a healthcare environment. [1] This includes a minimum level of standard precautions for use with all people regardless of their infection status, routine handwashing practices, safe handling and disposal of used needles and syringes, and intensifying standard precautions. It also includes VHF isolation precautions when needed. [1]

Limited supplies and resources may prevent a health facility from using all the standard precautions all the time. However, health facilities should establish and maintain a basic, practical level of standard precautions that can be used routinely with patients in their health facility. [1] This requires a source of clean water, routine handwashing before and after any contact with a person who has fever, and safe handling and disposal of sharp instruments and equipment. [1]

Washing hands with soap and water eliminates microorganisms from the skin and hands. This provides some protection against transmission of VHF and other diseases. [1] This requires at least cake soap cut into small pieces, soap dishes with openings that allow water to drain away, running water or a bucket kept full with clean water, a bucket for collecting rinse water and a ladle for dipping, if running water is not available, and one-use towels. [1]

The handwashing technique that is recommended is to place a piece of soap in the palm of one hand, wash the opposite hand and forearm, rub the surfaces vigorously for at least 10 seconds, move soap to the opposite hand and repeat, use clean water to rinse both hands and then the forearms, dry the hands and forearms with a clean one-use towel, or let rinsed hands and forearms air-dry. [1]

Reusable needles and syringes are not recommended. If reusable needles and syringes are used, clean, disinfect and sterilize them before reuse. Needles and syringes used with VHF patients require special care. Cleaning staff should wear two pairs of gloves when handling needles and syringes used with any patient with a known or suspected VHF. [1]

Identifying suspected cases

In an outbreak situation, several cases occur around the same time. They may be grouped together, and there may be person-to-person transmission. An initial diagnosis of a VHF can be made based on the signs and symptoms of the specific VHF.

Suspecting a VHF during a non-outbreak situation in a single case is more difficult. The early symptoms of a VHF include high fever and headache. These are also symptoms for many infections seen at the health facility. Most people who present with fever do not have a VHF. Their fever is more often caused by malaria, typhoid fever, dysentery, severe bacterial infection or other fever-producing illnesses usually seen in the area.

The health worker probably will not suspect a VHF until more severe signs develop and the patient does not respond to recommended treatment for other illnesses. However, health workers should be aware of the possibility of VHF in a non-outbreak situation. As soon as a VHF is suspected, VHF isolation precautions should begin. This will help reduce the number of people exposed to the VHF. [1]

Isolation

A sample layout of an isolation area Isolationroom.png
A sample layout of an isolation area

Isolating the VHF patient will restrict patient access to health facility staff trained to use VHF isolation precautions. Establish a barrier between the VHF patient and uninfected patients, other health facility staff, and visitors. [1]

Protective clothing

When a VHF case is suspected in the health facility, the following protective clothing should be worn in the isolation area:

When protective clothing is not available or is in short supply, adaptations must be made and used. [1]

Putting on

Steps for putting on protective clothing PuttingOnPPE.png
Steps for putting on protective clothing

There are specific recommendation regarding the putting on of protective clothing including: [1]

Taking off

Steps for taking off protective clothing TakingoffPPE.png
Steps for taking off protective clothing

There are also specific recommendations regarding the removal of protective clothing including: [1]

Disinfection of equipment

Disinfection kills almost all bacteria, fungi, viruses, and protozoa. It reduces the number of microorganisms to make equipment and surfaces safer for use. When VHF is suspected in the health facility, all medical, nursing, laboratory and cleaning staff should disinfect: [1]

Preparing bleach

Two strengths of solution are recommended. [1]

The dilutions mentioned pertain to a starting concentration of 5% active chlorine, so the 1:10 solution is 0.5% and the 1:100 is 0.05%.

These solutions must be prepared new each day as they lose their strength after 24 hours. [1]

Disposal of waste

A completed incinerator Incerneratorforvhf.png
A completed incinerator

Direct, unprotected contact during disposal of infectious waste can result in accidental transmission of VHF. For this reason, all contaminated waste produced in the care of the VHF patient must be disposed of safely. All non-reusable items should be destroyed so they cannot be used again. Burning should be carried out at least daily. [1]

Liquid waste, including patient excreta, can be disposed of in an isolated latrine or toilet set aside for VHF cases. Burning is the recommended method for disposal of other VHF-contaminated waste. A safe and inexpensive disposal system can be made by using an incinerator or a pit for burning. Use fuel to accelerate the burning and ensure that all waste is completely destroyed. [1]

Burial practices

Community education material regarding dead bodies and viral hemorrhagic fever BurialVHF.png
Community education material regarding dead bodies and viral hemorrhagic fever

There is risk of transmission in the health facility when a VHF patient dies because the bodies and body fluids of deceased VHF patients remain contagious for several days after death. Family and community members are also at risk if burial practices involve touching and washing the body. [1]

Burial should take place as soon as possible after the body is prepared in the health facility. Health facility staff should prepare the body safely and instruct families on what is and is not safe. [1]

To prepare the body, protective clothing is recommended per usually with a second pair of thick rubber gloves. The body and the area around it is sprayed with 1:10 bleach solution. The body is placed in a “body bag” (mortuary sack) and it is closed securely. The body bag is sprayed with 1:10 bleach solution. The body is then transported to the burial site as soon as possible. Any person who must touch or carry the body during transport should wear the same protective clothing as is worn in the isolation area. The grave should be at least 2 meters deep. Viewing the body is not possible and the burial ceremony should be limited to family only. The interior of the vehicle where the body was carried should be rinsed with 1:10 bleach solution. [1]

Community education

Community education and involvement is an important part of the prevention of the spread of VHF. [1]

Related Research Articles

Universal precautions standard preventive measures to be taken by professional and other health personnel in contact with persons afflicted with a communicable disease

Universal precautions refers to the practice, in medicine, of avoiding contact with patients' bodily fluids, by means of the wearing of nonporous articles such as medical gloves, goggles, and face shields. The practice was introduced in 1985–88. In 1987, the practice of universal precautions was adjusted by a set of rules known as body substance isolation. In 1996, both practices were replaced by the latest approach known as standard precautions. Use of personal protective equipment is now recommended in all health settings.

Biosafety level level of the biocontainment precautions required to isolate dangerous biological agents

A biosafety level (BSL) is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4). In the United States, the Centers for Disease Control and Prevention (CDC) have specified these levels. In the European Union, the same biosafety levels are defined in a directive. In Canada the four levels are known as Containment Levels. Facilities with these designations are also sometimes given as P1 through P4, as in the term "P3 laboratory".

Hygiene set of practices performed for the preservation of health

Hygiene is a series of practices performed to preserve health. According to the World Health Organization (WHO), "Hygiene refers to conditions and practices that help to maintain health and prevent the spread of diseases." Personal hygiene refers to maintaining the body's cleanliness.

Sodium hypochlorite Chemical compound

Sodium hypochlorite is a chemical compound with the formula NaOCl or NaClO, comprising a sodium cation and a hypochlorite anion. It may also be viewed as the sodium salt of hypochlorous acid. The anhydrous compound is unstable and may decompose explosively. It can be crystallized as a pentahydrate NaOCl·5H
2
O
, a pale greenish-yellow solid which is not explosive and is stable if kept refrigerated.

A blood-borne disease is a disease that can be spread through contamination by blood and other body fluids. Blood can contain pathogens of various types, chief among which are microorganisms, like bacteria and parasites, and non-living infectious agents such as viruses. Three bloodborne pathogens in particular, all viruses, are cited as of primary concern to health workers by the CDC-NIOSH: HIV, hepatitis B (HVB), & hepatitis C (HVC).

Operating theater facility within a hospital where surgical operations are carried out

An operating theater is a facility within a hospital where surgical operations are carried out in an aseptic environment.

Disinfectant Antimicrobial agents that inactivate or destroy microorganisms

Disinfectants are antimicrobial agents designed to inactivate or destroy microorganisms on inert surfaces. Disinfection does not necessarily kill all microorganisms, especially resistant bacterial spores; it is less effective than sterilization, which is an extreme physical and/or chemical process that kills all types of life. Disinfectants are different from other antimicrobial agents such as antibiotics, which destroy microorganisms within the body, and antiseptics, which destroy microorganisms on living tissue. Disinfectants are also different from biocides — the latter are intended to destroy all forms of life, not just microorganisms. Disinfectants work by destroying the cell wall of microbes or interfering with their metabolism.

Dishwashing process of cleaning dishes and cookware, generally using water and a detergent or soap

Dishwashing or dish washing, also known as washing up, is the process of cleaning cooking utensils, dishes, cutlery and other items to prevent foodborne illness. This is either achieved by hand in a sink using dishwashing detergent or by using a dishwasher and may take place in a kitchen, utility room, scullery or elsewhere. In Britain to do the washing up also includes to dry and put away. There are cultural divisions over rinsing and drying after washing.

Hospital-acquired infection Infection that is acquired in a hospital or other health care facility

A hospital-acquired infection (HAI), also known as a nosocomial infection, is an infection that is acquired in a hospital or other health care facility. To emphasize both hospital and nonhospital settings, it is sometimes instead called a health care–associated infection. Such an infection can be acquired in hospital, nursing home, rehabilitation facility, outpatient clinic, diagnostic laboratory or other clinical settings. Infection is spread to the susceptible patient in the clinical setting by various means. Health care staff also spread infection, in addition to contaminated equipment, bed linens, or air droplets. The infection can originate from the outside environment, another infected patient, staff that may be infected, or in some cases, the source of the infection cannot be determined. In some cases the microorganism originates from the patient's own skin microbiota, becoming opportunistic after surgery or other procedures that compromise the protective skin barrier. Though the patient may have contracted the infection from their own skin, the infection is still considered nosocomial since it develops in the health care setting.

Viral hemorrhagic fever type of illnesses

Viral hemorrhagic fevers (VHFs) are a diverse group of animal and human illnesses in which fever and hemorrhage are caused by a viral infection. VHFs may be caused by five distinct families of RNA viruses: the families Arenaviridae, Filoviridae, Bunyaviridae, Flaviviridae, and Rhabdoviridae. All types of VHF are characterized by fever and bleeding disorders and all can progress to high fever, shock and death in many cases. Some of the VHF agents cause relatively mild illnesses, such as the Scandinavian nephropathia epidemica, while others, such as Ebola virus, can cause severe, life-threatening disease.

Asepsis is the state of being free from disease-causing micro-organisms. The term often refers to those practices used to promote or induce asepsis in an operative field of surgery or medicine to prevent infection.

Infection control is the discipline concerned with preventing nosocomial or healthcare-associated infection, a practical sub-discipline of epidemiology. It is an essential, though often underrecognized and undersupported, part of the infrastructure of health care. Infection control and hospital epidemiology are akin to public health practice, practiced within the confines of a particular health-care delivery system rather than directed at society as a whole. Anti-infective agents include antibiotics, antibacterials, antifungals, antivirals and antiprotozoals.

Matthew Lukwiya Ugandan physician

Matthew Lukwiya was a Ugandan physician and the supervisor of St. Mary's Hospital Lacor, outside of Gulu. He was at the forefront of the 2000 Ebola virus disease outbreak in Uganda.

Biomedical waste/hospital waste is any kind of waste containing infectious materials. It may also include waste associated with the generation of biomedical waste that visually appears to be of medical or laboratory origin, as well research laboratory waste containing biomolecules or organisms that are mainly restricted from environmental release. As detailed below, discarded sharps are considered biomedical waste whether they are contaminated or not, due to the possibility of being contaminated with blood and their propensity to cause injury when not properly contained and disposed of. Biomedical waste is a type of biowaste.

Isolation (health care) various measures taken to prevent contagious diseases from being spread among patients, health care workers, and visitors

In health care facilities, isolation represents one of several measures that can be taken to implement infection control: the prevention of contagious diseases from being spread from a patient to other patients, health care workers, and visitors, or from outsiders to a particular patient. Various forms of isolation exist, in some of which contact procedures are modified, and others in which the patient is kept away from all others. In a system devised, and periodically revised, by the U.S. Centers for Disease Control and Prevention (CDC), various levels of patient isolation comprise application of one or more formally described "precaution".

Scrubs (clothing) lighweight, washable clothing worn by hospital staff or other medical personnel

Scrubs are the sanitary clothing worn by surgeons, nurses, physicians and other workers involved in patient care in hospitals. Originally designed for use by surgeons and other operating room personnel, who would put them on when sterilizing themselves, or "scrubbing in", before surgery, they are now worn by many hospital personnel. Their use has been extended outside hospitals as well, to work environments where clothing may come into contact with infectious agents. Scrubs are designed to be simple, easy to launder, and cheap to replace if damaged or stained irreparably. In the United Kingdom, scrubs are sometimes known as theatre blues.

Precautionary statements form part of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). They are intended to form a set of standardized phrases giving advice about the correct handling of chemical substances and mixtures, which can be translated into different languages. As such, they serve the same purpose as the well-known S-phrases, which they are intended to replace.

Barrier nursing is a largely archaic term for a set of stringent infection control techniques used in nursing. The aim of barrier nursing is to protect medical staff against infection by patients and also protect patients with highly infectious diseases from spreading their pathogens to other non-infected people.

Chlorine-releasing compounds family of chemicals that release chlorine used for disinfection

Chlorine-releasing compounds, also known as chlorine base compounds, are a family of chemicals that release chlorine. They are widely used to disinfect water, medical equipment, and surface areas as well as bleaching materials such as cloth. The presence of organic matter can make them less effective as disinfectants. They come as a powder that is mixed with water before use.

Single-use medical devices

Single-use medical devices include any medical equipment, instrument or apparatus having the ability to only be used once in a hospital or clinic and then disposed. The Food and Drug Administration defines this as any device entitled by its manufacturer that it is intended use is for one single patient and one procedure only. It is not reusable, therefore has a short lifespan, and is limited to one patient. There are countless types of single use medical devices, ranging from external, such as plastic gumboots, gloves and bandages merely used to assist a patient to more complex and internal devices, consisting of sharp blades, needles and tubes. Both these devices are single used, because of multiple reasons, but mainly, as it came in contact with radioactivity, blood, infection and disease or human tissue and must therefore be terminated. Each country has its own strict legislation regarding medical waste and the reprocessing of medical devices in hospitals and clinics.

References

  1. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Infection Control for Viral Haemorrhagic Fevers in the African Health Care Setting (PDF). World Health Organization and Centers for Disease Control and Prevention. December 1998. Retrieved 20 October 2014.

Infection Control for Viral Haemorrhagic Fevers in the African Health Care Setting (PDF). World Health Organization and Centers for Disease Control and Prevention. December 1998. Retrieved 20 October 2014.