Sapan Desai

Last updated
Sapan S. Desai
Born (1979-04-06) April 6, 1979 (age 45)
Evanston, Illinois, United States
Known for Surgisphere
Scientific career
FieldsMedicine

Sapan Sharankishor Desai (born April 6, 1979) is an American physician, and the owner of Surgisphere, originally a textbook marketing company that claimed to provide large sets of medical data on COVID-19 patients. This data and the research using it has been discredited, and two papers Desai co-authored that used this data were retracted after being published in prominent medical journals. [1]

Contents

Early life and education

Desai was born and raised in the North Shore (Chicago) region of Illinois by Indian parents. He is a graduate of the Stevenson High School (Lincolnshire, Illinois) and took 13 Advanced Placement classes there. Desai attended the University of Illinois at Chicago and studied biology, graduating at age 19. [2] He then joined the combined M.D./Ph.D. program at the University of Illinois College of Medicine. During this time, he completed his Ph.D. degree in anatomy and cell biology, and M.D. degree by age 27. [2] His doctoral adviser said that Desai claimed to be enrolled at John Marshall Law School, and later described himself as having his J.D., but there is no evidence of this being true. [2] A 2004 publication from his period in Chicago showed signs of data manipulation (numerous duplicated regions in photographs), upon re-examination in June 2020. [3]

He graduated in 2006, then matched to Duke University for residency as a general surgeon. [4] [5] In 2008 Desai, still a surgical resident, founded Surgisphere to market medical textbooks, produced by Surgisphere, to medical students. Fake 5-star reviews on Amazon from accounts impersonating physicians were found. [6] The Guardian noted that "in 2010, his Wikipedia page was flagged for deletion" because editors questioned his accomplishments. [7] The New York Times described him as an unreliable physician, and a chief resident from Duke said "You couldn't trust what he said. You would verify everything that he did and take everything he did with a grain of salt." Thirteen people interviewed by the New York Times said there were "broad concerns inside the surgery department" about Desai. He would make improbable claims about patients and wouldn't follow through on their care. [2]

Desai received his online M.B.A. degree in 2012 from Western Governors University in three months. [2] [8]

Career and further controversy

In 2012, Desai became a fellow in vascular surgery at the University of Texas Health Science Center at Houston. He published the Journal of Surgical Radiology, which closed in 2013 despite reportedly having accrued 50,000 subscribers, because he "ran out of time." The New York Times described his performance at the Texas hospital as problematic and having "antagonized some supervisors" to the point that they asked for him to be expelled, but he passed the program. Dr. Hazim Safi, the department chair, said "I intervened and he graduated", attributing the problems to personality, not skill. [6] From July 2014 to May 2016, Desai was a vascular surgeon at Southern Illinois University School of Medicine in charge of surgical simulation as vice chair of research. [9]

In February 2020, Desai resigned from Northwest Community Hospital in suburban Arlington Heights, Illinois "for family reasons"; at least four medical malpractice suits had been filed against him. [6] [2]

On June 4, 2020, in response to the fraud [10] found after the scrutiny of Surgisphere, its data, and after Surgisphere's inability to convince critics of their data's integrity, Desai joined his coauthors in retracting a paper from the New England Journal of Medicine . [11] The next day the three coauthors of another paper based on findings from Surgisphere data and published in The Lancet retracted the paper without Desai. [12] Dr. Richard Horton, editor in chief of The Lancet, called the paper a fabrication and "a monumental fraud". Dr. Eric Rubin, editor in chief of the New England Journal of Medicine, said "We shouldn’t have published this". [10] In late July 2020, the New York Times said people "described him as a man in a hurry, a former whiz kid willing to cut corners, misrepresent information or embellish his credentials as he pursued his ambitions." [2] The Lancet later revised its peer review procedures citing problems caused by Surgisphere's "alleged dataset". [13] [14]

Subsequently, Elisabeth Bik analyzed one of Desai's early first author papers and found evidence of apparent image manipulation. [3] [15]

Personal life

Desai is related to his co-author, physician Amit Patel, by marriage. [16]

Related Research Articles

Scientific misconduct is the violation of the standard codes of scholarly conduct and ethical behavior in the publication of professional scientific research. It is violation of scientific integrity: violation of the scientific method and of research ethics in science, including in the design, conduct, and reporting of research.

<i>The Lancet</i> Peer-reviewed general medical journal

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In academic publishing, a retraction is a mechanism by which a published paper in an academic journal is flagged for being seriously flawed to the extent that their results and conclusions can no longer be relied upon. Retracted articles are not removed from the published literature but marked as retracted. In some cases it may be necessary to remove an article from publication, such as when the article is clearly defamatory, violates personal privacy, is the subject of a court order, or might pose a serious health risk to the general public.

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<span class="mw-page-title-main">Oriol Mitjà</span> Catalan researcher

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Surgisphere is an American healthcare analytics company established in 2008 by Sapan Desai. Originally a textbook marketing company, it came under scrutiny in May 2020 after it provided large datasets of COVID-19 patients that were subsequently found to be unreliable. The questionable data were used in studies published in The Lancet and The New England Journal of Medicine in May 2020, suggesting that COVID-19 patients on hydroxychloroquine had a "significantly higher risk of death". In light of these studies, the World Health Organization decided to temporarily halt global trials of the drug hydroxychloroquine to treat COVID-19. After the studies were retracted, the WHO trials were resumed and then discontinued shortly after.

Sir Martin Jonathan Landray is a British physician, epidemiologist and data scientist who serves as a Professor of Medicine & Epidemiology at the University of Oxford. Landray designs, conducts and analyses large-scale randomised control trials; including practice-changing international trials that have recruited over 100,000 individuals. Landray previously led the health informatics team that enabled the collection and management of data for the UK Biobank on over half a million people.

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References

  1. ↑ Aldhous, Peter; Lee, Stephanie M. (6 June 2020). "Scientists Are Questioning Past Research By The Founder of Surgisphere". BuzzFeed News . Retrieved 7 June 2020.
  2. 1 2 3 4 5 6 7 Ellen Gabler; Roni Caryn Rabin (27 July 2020). "The Doctor Behind the Disputed Covid Data". The New York Times . Retrieved 27 July 2020.
  3. 1 2 Elisabeth Bik (2020-06-06). "The Surgisphere Founder and the Melba Toast figure". Science Integrity Digest. Retrieved 2020-06-08.
  4. ↑ "Alumni". Chicago Medicine. Retrieved 6 June 2020. Sapan Desai (2006) PhD: Anatomy & Cell Biology ; Thesis Advisor: Anna Lysakowski, PhD Residency: General Surgery, Duke University
  5. ↑ "University of Illinois College of Medicine at Chicago Match Results". Chicago Medicine. Retrieved 6 June 2020.
  6. 1 2 3 Offord, Catherine (2020-05-30). "Disputed Hydroxychloroquine Study Brings Scrutiny to Surgisphere". The Scientist Magazine®. Retrieved 2020-06-08.
  7. ↑ Davey, Melissa; Kirchgaessner, Stephanie; Boseley, Sarah (2020-06-03). "Surgisphere: governments and WHO changed Covid-19 policy based on suspect data from tiny US company". The Guardian. ISSN   0261-3077 . Retrieved 2020-07-07.
  8. ↑ "Online MBA Graduate Sapan Desai, MD, Ph.D. - A WGU Success Story". YouTube. Western Governors University. 2012. Retrieved 9 June 2020.
  9. ↑ Roberta Bernstein (25 September 2015). "Medical Scientist MD-PHD UIC newsletter vol 16 issue 1" (PDF). chicago.medicine.uic.edu. Retrieved 6 June 2020.
  10. 1 2 Roni Caryn Rabin (14 June 2020). "The Pandemic Claims New Victims: Prestigious Medical Journals". The New York Times . Retrieved 18 June 2020.
  11. ↑ Mehra, Mandeep R.; Desai, Sapan S.; Kuy, SreyRam; Henry, Timothy D.; Patel, Amit N. (4 June 2020). "Retraction: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med. DOI: 10.1056/NEJMoa2007621". New England Journal of Medicine. 382 (26): 2582. doi:10.1056/NEJMc2021225. PMC   7274164 . PMID   32501665.
  12. ↑ Mehra, Mandeep R; Ruschitzka, Frank; Patel, Amit N (5 June 2020). "Retraction—Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis". The Lancet. 395 (10240): 1820. doi:10.1016/S0140-6736(20)31324-6. PMC   7274621 . PMID   32511943.
  13. ↑ The Editors Of The Lancet Group (17 September 2020). "Learning from a retraction". The Lancet. 396 (10257): 1056. doi:10.1016/S0140-6736(20)31958-9. PMC   7498225 . PMID   32950071.{{cite journal}}: |last1= has generic name (help)
  14. ↑ Hopkins, Jared S. (18 September 2020). "Lancet Medical Journal Changes Peer-Review Process Amid Flurry of Covid-19 Research". The Wall Street Journal. Retrieved 18 September 2020.
  15. ↑ Davey, Melissa; Kirchgaessner, Stephanie (2020-06-10). "Surgisphere: mass audit of papers linked to firm behind hydroxychloroquine Lancet study scandal". The Guardian. Retrieved 2020-06-10.
  16. ↑ Piller, Charles (2020-06-08). "Who's to blame? These three scientists are at the heart of the Surgisphere COVID-19 scandal" . Retrieved 2020-07-07.
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