The Scar Free Foundation

Last updated
The Scar Free Foundation
Established1998
FounderMichael Brough
TypeMedical research charity
FocusWound healing and scarring conditions
Headquarters The Royal College of Surgeons of England
Chairman
Professor Sir Bruce Keogh
Chief Executive
Lieutenant General Richard Nugee CBE
Royal Patron
Sophie, Duchess of Edinburgh
Website Official website
Formerly called
The Healing Foundation

The Scar Free Foundation is a medical research charity focused on scar free healing. [1] It was founded in 1998 by plastic surgeon Michael Brough, following his work with survivors of the King's Cross Fire in London. Initially known as The Healing Foundation, it was relaunched as The Scar Free Foundation in 2016.

Contents

The charity funds medical research into wound healing and scarring conditions. Current research is focused on identifying the pathways that lead to scarring, developing new treatment options, and improving the psychological outcomes and quality of life of patients currently living with scars.

The current Chairman is former Medical Director of the NHS, Sir Bruce Keogh, and the Chief Executive is Richard Nugee CB CVO CBE. Peter Weissberg CBE is the Research Council Chairman. Sophie, Duchess of Edinburgh is the charity's Royal Patron. Notable Ambassadors include Simon Weston CBE and Pam Warren.

History

Phoenix Appeal

Mr Michael Brough was the leading surgeon at the University College Hospital on 18 November 1987, when a wooden escalator at the King's Cross underground station burst into flames. [2] The intense fire in a confined space resulted in 31 deaths; 19 survivors suffered flame burns. [3]

Inspired by his experiences, Brough initiated efforts to improve treatment for the physical and psychological impact of burns. He set up the Phoenix Appeal in 1988 to fund the establishment of the first university department of plastic and reconstructive surgery at University College London. [4]

The Healing Foundation

In 1998, as Treasurer of the British Association of Plastic, Reconstructive, and Aesthetic Surgeons (BAPRAS), Brough and his fellow Trustees established The Healing Foundation. [5] [6] Building on the groundwork laid by the Phoenix Appeal, The Healing Foundation aimed to advance research into surgical and psychological healing techniques for individuals with disfiguring conditions.

Various UK medical membership bodies provided support to The Healing Foundation as Partner Member Organisations. These partnerships bolstered the charity's credibility, networking capabilities, and financial resources.These organisations were BAPRAS, the British Association of Aesthetic Surgeons, [7] the British Psychological Society, [8] the Craniofacial Society of Great Britain and Ireland, [9] the British Burns Association, [10] and the British Society for Surgery of the Hand. [11]

Chief Executive Richard Nugee speaking to Scar Free Foundation Ambassadors at an event at the Royal College of Surgeons in 2023. Lt Gen (rtd) Richard Nugee at Scar Free Foundation Ambassador Event October 2023.jpg
Chief Executive Richard Nugee speaking to Scar Free Foundation Ambassadors at an event at the Royal College of Surgeons in 2023.

John Hart CBE was appointed as the first Director of The Healing Foundation in February 1999. [6] Brendan Eley joined the organisation as Appeal Director in 2001, before being made CEO in 2004. [6]

Notable Research Chairmen for The Healing Foundation include Sir Kenneth Calman and Sir John Temple. Notable Trustees include Sir Stuart Rose and Chris Patten.

The Scar Free Foundation

In 2016, The Healing Foundation officially rebranded as The Scar Free Foundation. [12] This change was made following a detailed assessment of previous work and future priorities with clinicians, scientists, Partner Member Organisations, and people with lived experience of scarring. [6] The charity pivoted to focus exclusively on wound healing and scarring conditions. A new Research Strategy was developed by a panel chaired by Professor Sir John Iredale.

Brendan Eley was succeeded as CEO by Richard Nugee in April 2023. [13]

Research Centres and Major Projects

The Scar Free Foundation (formerly The Healing Foundation) has co-ordinated research projects in burns, cleft, conflict wounds, and scarring genetics since its inception in 1998. Notable projects include:

Burns

The Healing Foundation facilitated the establishment of two research centres dedicated to burns. The first, situated at Frenchay Hospital in Bristol, aimed to develop innovative techniques for burn prevention and enhance clinical care for affected children. [14] [15] The Centre for Children's Burns Research was officially opened in June 2013 by Sophie, Duchess of Edinburgh.

Subsequently, another research hub, the Healing Foundation Centre for Burns Research, was inaugurated at Queen Elizabeth Hospital in Birmingham in October 2013. [16]

A notable outcome of The Healing Foundation Centre for Children's Burns Research was the SmartWound PREDICT Dressing, developed by scientists at the University of Bath. This dressing changes colour upon detecting bacteria, providing an alternative method for infection detection. [17]

Cleft

The Scar Free Foundation initiated the Cleft Collective, a large-scale multigenerational cohort study investigating the causes, treatments, and long-term outcomes of children born with cleft lip and/or palate. [18] With over 10,000 participants recruited from all 16 Cleft Centres in the UK, the project stands as the largest biobank of its kind globally. [19] The collected data is available for researchers from various disciplines, resulting in numerous peer-reviewed publications. [20]

Conflict Wounds

In 2018, the Scar Free Foundation Centre for Conflict Wound Research was established at the Royal Centre for Defence Medicine in Queen Elizabeth Hospital, Birmingham. [21] The centre's studies aim to mitigate the physical and psychological impacts of scarring among servicemen, women, and individuals injured in terrorist attacks. It was established in partnersip with the CASEVAC Club, a members organisation similar to the Guinea Pig Club.

Regenerative Research

The Healing Foundation Centre at the University of Manchester was opened in 2007. [22] It was focused on understanding wound healing and tissue regeneration mechanisms, with notable discoveries including the identification of genes activated during tissue regeneration in animals. [23] [24]

Additionally, the Scar Free Foundation co-funded the 3D BioFace project at Swansea University. [25] This ongoing initiative employs 3D bioprinting technology to reconstruct facial cartilage, offering less invasive and more personalised solutions for patients requiring facial reconstruction, such as those with microtia or bosma arhinia microphthalmia syndrome. [26]

Psychology

The Healing Foundation funded research programs aimed at understanding the psychological impact of visible differences, such as scarring and limb loss from conflict.

Notable projects include the Appearance Research Collaboration, which focused on identifying psychological factors contributing to successful adjustment to life with a visible difference. [27] The result of this programme of research was the publication of CBT-based intervention manual for professionals working with people with visible differences.

Also notable is UNITS, the first study to assess the psychological impact of altered appearance due to scarring and limb loss sustained during military conflict. Led by Dr. Mary Keeling at the University of the West of England, this study aimed to develop tailored support materials for affected veterans and their families. [28]

Related Research Articles

<span class="mw-page-title-main">Plastic surgery</span> Medical surgical specialty

Plastic surgery is a surgical specialty involving the restoration, reconstruction, or alteration of the human body. It can be divided into two main categories: reconstructive surgery and cosmetic surgery. Reconstructive surgery includes craniofacial surgery, hand surgery, microsurgery, and the treatment of burns. While reconstructive surgery aims to reconstruct a part of the body or improve its functioning, cosmetic surgery aims to improve the appearance of it. A comprehensive definition of plastic surgery has never been established, because it has no distinct anatomical object and thus overlaps with practically all other surgical specialties. An essential feature of plastic surgery is that it involves the treatment of conditions that require or may require tissue relocation skills.

<span class="mw-page-title-main">Scar</span> Area of fibrous tissue that replaces normal skin after an injury

A scar is an area of fibrous tissue that replaces normal skin after an injury. Scars result from the biological process of wound repair in the skin, as well as in other organs, and tissues of the body. Thus, scarring is a natural part of the healing process. With the exception of very minor lesions, every wound results in some degree of scarring. An exception to this are animals with complete regeneration, which regrow tissue without scar formation.

<span class="mw-page-title-main">Simon Weston</span> Welsh soldier and charity worker

Simon Weston is a Welsh veteran of the British Army who is known for his charity work and recovery from severe burn injuries suffered during the Falklands War.

<span class="mw-page-title-main">Healing</span> Process of the restoration of health

With physical trauma or disease suffered by an organism, healing involves the repairing of damaged tissue(s), organs and the biological system as a whole and resumption of (normal) functioning. Medicine includes the process by which the cells in the body regenerate and repair to reduce the size of a damaged or necrotic area and replace it with new living tissue. The replacement can happen in two ways: by regeneration in which the necrotic cells are replaced by new cells that form "like" tissue as was originally there; or by repair in which injured tissue is replaced with scar tissue. Most organs will heal using a mixture of both mechanisms.

<span class="mw-page-title-main">Rhinoplasty</span> Surgical procedure to enhance or reconstruct a human nose

Rhinoplasty, commonly called nose job, medically called nasal reconstruction, is a plastic surgery procedure for altering and reconstructing the nose. There are two types of plastic surgery used – reconstructive surgery that restores the form and functions of the nose and cosmetic surgery that changes the appearance of the nose. Reconstructive surgery seeks to resolve nasal injuries caused by various traumas including blunt, and penetrating trauma and trauma caused by blast injury. Reconstructive surgery can also treat birth defects, breathing problems, and failed primary rhinoplasties. Rhinoplasty may remove a bump, narrow nostril width, change the angle between the nose and the mouth, or address injuries, birth defects, or other problems that affect breathing, such as a deviated nasal septum or a sinus condition. Surgery only on the septum is called a septoplasty.

<span class="mw-page-title-main">Wound healing</span> Series of events that restore integrity to damaged tissue after an injury

Wound healing refers to a living organism's replacement of destroyed or damaged tissue by newly produced tissue.

<span class="mw-page-title-main">Archibald McIndoe</span> New Zealand plastic surgeon

Sir Archibald Hector McIndoe was a New Zealand plastic surgeon who worked for the Royal Air Force during the Second World War. He improved the treatment and rehabilitation of badly burned aircrew.

<span class="mw-page-title-main">Skin grafting</span> Surgical transplantation of skin

Skin grafting, a type of graft surgery, involves the transplantation of skin. The transplanted tissue is called a skin graft.

<span class="mw-page-title-main">Regenerative medicine</span> Field of medicine involved in regenerating tissues

Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs.

ReSurge International, formerly known as Interplast, is an international humanitarian organization that provides free reconstructive surgery in developing countries, primarily to children with cleft lip and palate and burn scar contractures.

Peter Edward Michael Butler, FRCSI, FRCS, FRCS (Plast) is Professor of Plastic and Reconstructive Surgery at University College London. He is consultant plastic surgeon and head of the face transplantation team at the Royal Free London NHS Foundation Trust in London, United Kingdom. He is Director of the Charles Wolfson Center for Reconstructive Surgery at the Royal Free Hospital, which was launched in November by The Right Honourable George Osborne, MP, Chancellor of the Exchequer at No 11 Downing Street in November 2013.

<span class="mw-page-title-main">Wexham Park Hospital</span> Hospital in Berkshire, England

Wexham Park Hospital is a large NHS hospital in Slough, Berkshire. It has been managed by Frimley Health NHS Foundation Trust since 2014. Neil Dardis has been the Trust's chief executive since 2018.

Aesthetic medicine is a branch of modern medicine that focuses on altering natural or acquired unwanted appearance through the treatment of conditions including scars, skin laxity, wrinkles, moles, liver spots, excess fat, cellulite, unwanted hair, skin discoloration, spider veins and or any unwanted externally visible appearance. Traditionally, it includes dermatology, oral and maxillofacial surgery, reconstructive surgery and plastic surgery, surgical procedures, non-surgical procedures, and a combination of both. Aesthetic medicine procedures are usually elective. There is a long history of aesthetic medicine procedures, dating back to many notable cases in the 19th century, though techniques have developed much since then.

<span class="mw-page-title-main">Fiona Wood</span> Australian plastic surgeon and burns specialist

Fiona Melanie Wood is an Australian plastic surgeon and burns specialist working in Perth, Western Australia. She is the director of the Royal Perth Hospital burns unit and the Western Australia Burns Service, and developed spray-on skin in collaboration with Marie Stoner. In addition, Wood is also a clinical professor with the School of Paediatrics and Child Health at the University of Western Australia and director of the Fiona Wood Foundation.

<span class="mw-page-title-main">Pam Warren (speaker)</span>

Pam Warren is a professional speaker and author who became known in the United Kingdom as the 'Lady in the Mask' after receiving severe burn injuries in the Ladbroke Grove rail crash in 1999. She is the founder of the Paddington Survivors Group. She is a spokesperson and advocate for railway safety and the author of From Behind the Mask, a memoir of her life during and after the train collision.

Regeneration in humans is the regrowth of lost tissues or organs in response to injury. This is in contrast to wound healing, or partial regeneration, which involves closing up the injury site with some gradation of scar tissue. Some tissues such as skin, the vas deferens, and large organs including the liver can regrow quite readily, while others have been thought to have little or no capacity for regeneration following an injury.

Peter Leslie Weissberg is a British physician.

Scar free healing is the process by which significant injuries can heal without permanent damage to the tissue the injury has affected. In most healing, scars form due to the fibrosis and wound contraction, however in scar free healing, tissue is completely regenerated. During the 1990s, published research on the subject increased; it is a relatively recent term in the literature. Scar free healing occurs in foetal life but the ability progressively diminishes into adulthood. In other animals such as amphibians, however, tissue regeneration occurs, for example as skin regeneration in the adult axolotl.

<span class="mw-page-title-main">Integra LifeSciences</span> Device manufacturing company

Integra LifeSciences is a global medical device manufacturing company headquartered in Princeton, New Jersey. Founded in 1989, the company manufactures products for skin regeneration, neurosurgery, reconstructive and general surgery. Integra artificial skin became the first commercially reproducible skin tissue used to treat severe burns and other skin wounds.

Anthony Howard Norman Roberts OBE. OStJ FRCS FRCSG FRSB FRGS is a British retired plastic and reconstructive surgeon. He was a consultant plastic and hand surgeon at Stoke Mandeville Hospital, Buckinghamshire from 1985 to 2001, and director of the Oxford regional burn unit at Stoke Mandeville Hospital. He then worked for periods for the Ministry of Defence as a plastic surgeon and as a general surgeon during the years 2001 to 2005.

References

  1. "About Us — The Scar Free Foundation". scarfree.org.uk. Retrieved 2024-01-09.
  2. "King's Cross fire: 'I was screaming in pain'". BBC News. 2017-11-18. Retrieved 2024-01-09.
  3. Croome, Desmond F.; Jackson, Alan Arthur (1993). Rails Through the Clay: A History of London's Tube Railways. Capital Transport. ISBN 978-1-85414-151-4. p459
  4. "Michael Brough". The Independent. 2004-12-13. Retrieved 2024-01-09.
  5. "About Us | BAPRAS". www.bapras.org.uk. Retrieved 2024-01-09.
  6. 1 2 3 4 Hart, John; Eley, Brendan (2016). Green, A. Roger (ed.). BAPS to BAPRAS: The History of the Association 1986-2016. London: Polymath Publishing. pp. 137–142. ISBN   978-1-904096-29-0.
  7. "British Association of Aesthetic Plastic Surgeons (BAAPS) — The Scar Free Foundation". scarfree.org.uk. Retrieved 2024-01-09.
  8. "The British Psychological Society — The Scar Free Foundation". scarfree.org.uk. Retrieved 2024-01-09.
  9. "The Scar Free Foundation". craniofacialsociety.co.uk. Retrieved 2024-01-09.
  10. "The British Burn Association — The Scar Free Foundation". scarfree.org.uk. Retrieved 2024-01-09.
  11. "The Scar Free Foundation | The British Society for Surgery of the Hand". www.bssh.ac.uk. Retrieved 2024-01-09.
  12. Bristol, University of. "July: scar-free healing | News and features | University of Bristol". www.bristol.ac.uk. Retrieved 2024-01-09.
  13. "About Us — The Scar Free Foundation". scarfree.org.uk. Retrieved 2024-01-09.
  14. "Frenchay Hospital children's burns research centre opens". BBC News. 2013-06-10. Retrieved 2024-01-10.
  15. Bristol, University of. "2013: School of Social and Community Medicine | News and features | University of Bristol". www.bristol.ac.uk. Retrieved 2024-01-10.
  16. Buckley, Jemma (2014-10-21). "Countess of Wessex opens Birmingham burns research centre". Birmingham Live. Retrieved 2024-01-10.
  17. Hickey, Shane (2015-12-20). "The innovators: colour-changing bandage to help fight antibiotic resistance". The Guardian. ISSN   0261-3077 . Retrieved 2024-01-22.
  18. "Cleft lip research launched in UK". BBC News. 2012-03-26. Retrieved 2024-01-10.
  19. Bristol, University of. "2022: 10,000th Participant and Funding News! | Bristol Dental School | University of Bristol". www.bristol.ac.uk. Retrieved 2024-01-10.
  20. Bristol, University of. "Publications". www.bristol.ac.uk. Retrieved 2024-01-10.
  21. "Britain's first specialist wound hub to open". BBC News. 2018-11-13. Retrieved 2024-01-10.
  22. "Burns victims research hub opens". 2007-09-13. Retrieved 2024-01-22.
  23. Love, Nick R.; Chen, Yaoyao; Bonev, Boyan; Gilchrist, Michael J.; Fairclough, Lynne; Lea, Robert; Mohun, Timothy J.; Paredes, Roberto; Zeef, Leo AH; Amaya, Enrique (2011-11-15). "Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration". BMC Developmental Biology. 11 (1): 70. doi: 10.1186/1471-213X-11-70 . ISSN   1471-213X. PMC   3247858 . PMID   22085734.
  24. Love, Nick R.; Chen, Yaoyao; Ishibashi, Shoko; Kritsiligkou, Paraskevi; Lea, Robert; Koh, Yvette; Gallop, Jennifer L.; Dorey, Karel; Amaya, Enrique (February 2013). "Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration". Nature Cell Biology. 15 (2): 222–228. doi:10.1038/ncb2659. ISSN   1465-7392. PMC   3728553 . PMID   23314862.
  25. "3D printing: Ears and noses to be created using human cells". BBC News. 2022-03-11. Retrieved 2024-01-11.
  26. Tyrer-Jones, Alex (2023-04-04). "3D printed vegan nose developed by scientists at Swansea University". 3D Printing Industry. Retrieved 2024-01-11.
  27. Rumsey, Nicola; Bryon-Daniel, James; Charlton, Rodger; Clarke, Alex; Harcourt, Diana (2009). "Identifying the psychosocial factors and processes contributing to successful adjustment to disfiguring conditions: Final Report". The Appearance Research Collaboration. et al, by The Appearance Research Collaboration. University of the West of England.
  28. Keeling, M.; Williams, V. S.; Harcourt, D.; Kiff, J.; Williamson, H. (2023-12-18). "Mothers' Experiences of Their Sons' Appearance-Altering Combat Injuries: Distressed and Unsupported". Military Behavioral Health: 1–12. doi: 10.1080/21635781.2023.2293896 . ISSN   2163-5781.