Human enhancement

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Human enhancement is the natural, artificial, or technological alteration of the human body in order to enhance physical or mental capabilities. [1]

Contents

Technologies

Existing technologies

Gene therapy using an adenovirus vector Gene therapy.jpg
Gene therapy using an adenovirus vector

Three forms of human enhancement currently exist: reproductive, physical, and mental. Reproductive enhancements include embryo selection by preimplantation genetic diagnosis, cytoplasmictransfer, and in vitro-generated gametes. Physical enhancements include cosmetics (plastic surgery and orthodontics), Drug-induced (doping and performance-enhancing drugs), functional (prosthetics and powered exoskeletons), Medical (implants (e.g. pacemaker) and organ replacements (e.g. bionic lenses)), and strength training (weights (e.g. barbells) and dietary supplement)). Examples of mental enhancements are nootropics, neurostimulation, and supplements that improve mental functions. [2] [3] Computers, mobile phones, and Internet [4] can also be used to enhance cognitive efficiency. Notable efforts in human augmentation are driven by the interconnected Internet of Things (IoT) devices, [5] including wearable electronics (e.g., augmented reality glasses, smart watches, smart textile), personal drones, on-body and in-body nanonetworks. [6]

Emerging technologies

Many different forms of human enhancing technologies are either on the way or are currently being tested and trialed. A few of these emerging technologies include: human genetic engineering (gene therapy), neurotechnology (neural implants and brain–computer interfaces), cyberware, strategies for engineered negligible senescence, nanomedicine, and 3D bioprinting. Variants of human genetic engineering with so far limited usage include the artificial creation of human-animal hybrids (where each cell has partly human and partly animal genetic contents) and human-animal chimeras (where some cells are human and some cells are animal in origin). [7] [ better source needed ]

Speculative technologies

Some other human enhancement technologies are still speculative, such as: mind uploading, exocortex, and endogenous artificial nutrition. Mind uploading is the hypothetical process of "transferring"/"uploading" or copying a conscious mind from a brain to a non-biological substrate by scanning and mapping a biological brain in detail and copying its state into a computer system or another computational device. The exocortex can be defined as a theoretical artificial external information processing system that would augment a brain's biological high-level cognitive processes. Endogenous artificial nutrition can be similar to having a radioisotope generator that resynthesizes glucose (similarly to photosynthesis), amino acids and vitamins from their degradation products, theoretically availing for weeks without food if necessary.

Nick Bostrom listed some additional capabilities that are expected to be physically possible in theory, given a sufficient technological level, such as: [8]

Nootropics

There are many substances that are purported to have promise in augmenting human cognition by various means. These substances are called nootropics and can potentially benefit individuals with cognitive decline and many different disorders, but may also be capable of yielding results in cognitively healthy persons. Generally speaking, nootropics are said to be effective for enhancing focus, learning, memory function, mood, and in some cases, physical brain development. Some examples of these include Citicoline, [9] Huperzine A, Phosphatidylserine, [10] Bacopa monnieri, [11] Acetyl-L-carnitine, [12] Uridine monophosphate, L-theanine, [13] [14] [15] Rhodiola rosea, and Pycnogenol which are all forms of dietary supplement. There are also nootropic drugs such as the common racetams, e.g. piracetam (Nootropil) and omberacetam (Noopept) [16] [17] [18] along with the neuroprotective Semax, and N-Acetyl Semax. [19] There are also nootropics related to naturally occurring substances but that are either modified in a lab or are analogs such as Vinpocetine and Sulbutiamine. Some authors have explored nootropics as relationship enhancements to help couples maintain bonds over time. [20]

Ethics

Much debate surrounds the topic of human enhancement and the means used to achieve one's enhancement goals. [21] Ethical attitudes toward human enhancement can depend on many factors such as religious affiliation, age, gender, ethnicity, culture of origin, and nationality. [22]

In some circles the expression "human enhancement" is roughly synonymous with human genetic engineering, [23] [24] but most often it is referred to the general application of the convergence of nanotechnology, biotechnology, information technology and cognitive science (NBIC) to improve human performance. [25]

Since the 1990s, several academics (such as some of the fellows of the Institute for Ethics and Emerging Technologies [26] ) have risen to become advocates of the case for human enhancement while other academics (such as the members of President Bush's Council on Bioethics [27] ) have become outspoken critics. [28]

Advocacy of the case for human enhancement is increasingly becoming synonymous with "transhumanism", a controversial ideology and movement which has emerged to support the recognition and protection of the right of citizens to either maintain or modify their own minds and bodies; so as to guarantee them the freedom of choice and informed consent of using human enhancement technologies on themselves and their children. [29] Their common understanding of the world can be seen from a physicist perspective rather than a biological perspective. [30] Based on the idea of technological singularity, human enhancement is merging with technological innovation that will advance post-humanism. [30]

Neuromarketing consultant Zack Lynch argues that neurotechnologies will have a more immediate effect on society than gene therapy and will face less resistance as a pathway of radical human enhancement. He also argues that the concept of "enablement" needs to be added to the debate over "therapy" versus "enhancement". [31]

The prospect of human enhancement has sparked public controversy. [32] [33] [34] The main ethical question in the debate about human enhancement involves which legal restrictions, if any, should exist. [35]

Dale Carrico wrote that "human enhancement" is a loaded term which has eugenic overtones because it may imply the improvement of human hereditary traits to attain a universally accepted norm of biological fitness (at the possible expense of human biodiversity and neurodiversity), and therefore can evoke negative reactions far beyond the specific meaning of the term. [36] Michael Selgelid terms this as a phase of "neugenics" suggesting that gene enhancements occurring now have already revived the idea of eugenics in our society. Practices of prenatal diagnosis, selective abortion and in-vitro fertilization aims to improve human life allowing for parents to decide via genetic information if they want to continue or terminate the pregnancy. [37]

A criticism of human enhancement is that it will create unfair physical or mental advantages, or unequal access to such enhancements, can and will further the gulf between the "haves" and "have-nots". [38] [39] [40] [41]

Futurist Ray Kurzweil has shown some concern that, within the century, humans may be required to merge with this technology in order to compete in the marketplace. [30] Enhanced individuals have a better chance of being chosen for better opportunities in careers, entertainment and resources. [42] For example, life extending technologies can increase the average individual life span, affecting the distribution of pension throughout the society. Increasing lifespan will affect human population, further dividing limited resources such as food, energy, monetary resources and habitat. [42] Other critics of human enhancement fear that such capabilities would change, for the worse, the dynamic relations within a family. Given the choices of superior qualities, parents make their child as opposed to merely birthing it, and the newborn becomes a product of their will rather than a gift of nature to be loved unconditionally. [43]

Effects on identity

Human enhancement technologies can impact human identity by affecting one's self-conception. [44] The argument does not necessarily come from the idea of improving the individual but rather changing who they are and becoming someone new. Altering an individual identity affects their personal story, development and mental capabilities. The basis of this argument comes from two main points : the charge of inauthenticity and the charge of violating an individual's core characteristics. [44] Gene therapy has the ability to alter one’s mental capacity, and through this argument, has the ability to affect their narrative identity. [44] An individual's core characteristics may include internal psychological style, personality, general intelligence, necessity to sleep, normal aging, gender and being Homo sapiens . Technologies threaten to alter the self fundamentally to the point where the result is, essentially, a different person entirely. [44] For example, extreme changes in personality may affect the individual's relationships because others can no longer relate to the new person. [41]

The capability approach focuses on a normative framework that can be applied to how human enhancement technologies affects human capabilities. [45] The ethics of this does not necessarily focus on the make up of the individual but rather what it allows individuals to do in today's society. This approach was first termed by Amartya Sen, where he mainly focused on the objectives of the approach rather than the aim for those objectives which entail resources, technological processes, and economic arrangement. [45] The central human capabilities include life, bodily health, bodily integrity, sense, emotions, practical reason, affiliation, other species, play, and control over one's environment. This normative framework recognizes that human capabilities are always changing and technology has already played a part in this. [45]

See also

Related Research Articles

Transhumanism is a philosophical and intellectual movement that advocates the enhancement of the human condition by developing and making widely available sophisticated technologies that can greatly enhance longevity, cognition, and well-being.

The term superhuman refers to humans, human-like beings or beings with qualities and abilities that exceed those naturally found in humans. These qualities may be acquired through natural ability, self-actualization or technological aids. The related concept of a super race refers to an entire category of beings with the same or varying superhuman characteristics, created from present-day human beings by deploying various means such as eugenics, euthenics, genetic engineering, nanotechnology, and/or brain–computer interfacing to accelerate the process of human evolution.

<span class="mw-page-title-main">Nootropic</span> Compound intended to improve cognitive function

Nootropics, colloquially brain supplements, smart drugs and cognitive enhancers, are natural, semisynthetic or synthetic compounds which purportedly improve cognitive functions, such as executive functions, attention or memory.

In philosophy and neuroscience, neuroethics is the study of both the ethics of neuroscience and the neuroscience of ethics. The ethics of neuroscience concerns the ethical, legal and social impact of neuroscience, including the ways in which neurotechnology can be used to predict or alter human behavior and "the implications of our mechanistic understanding of brain function for society... integrating neuroscientific knowledge with ethical and social thought".

A superintelligence is a hypothetical agent that possesses intelligence far surpassing that of the brightest and most gifted human minds. "Superintelligence" may also refer to a property of problem-solving systems whether or not these high-level intellectual competencies are embodied in agents that act in the world. A superintelligence may or may not be created by an intelligence explosion and associated with a technological singularity.

<span class="mw-page-title-main">Human genetic enhancement</span> Technologies to genetically improve human bodies

Human genetic enhancement or human genetic engineering refers to human enhancement by means of a genetic modification. This could be done in order to cure diseases, prevent the possibility of getting a particular disease, to improve athlete performance in sporting events, or to change physical appearance, metabolism, and even improve physical capabilities and mental faculties such as memory and intelligence. These genetic enhancements may or may not be done in such a way that the change is heritable.

Cognitive liberty, or the "right to mental self-determination", is the freedom of an individual to control their own mental processes, cognition, and consciousness. It has been argued to be both an extension of, and the principle underlying, the right to freedom of thought. Though a relatively recently defined concept, many theorists see cognitive liberty as being of increasing importance as technological advances in neuroscience allow for an ever-expanding ability to directly influence consciousness. Cognitive liberty is not a recognized right in any international human rights treaties, but has gained a limited level of recognition in the United States, and is argued to be the principle underlying a number of recognized rights.

<span class="mw-page-title-main">Theanine</span> Amino acid

Theanine, commonly known as L-theanine and sometimes L-gamma-glutamylethylamide or N5-ethyl-L-glutamine, is an amino acid analogue of the proteinogenic amino acids L-glutamate and L-glutamine and is found primarily in particular plant and fungal species. It was discovered as a constituent of green tea in 1949 and isolated from gyokuro leaves in 1950, thus rendering it a natural product. It constitutes about 1–2% of the dry weight of green tea leaves.

Neurohacking is a subclass of biohacking, focused specifically on the brain. Neurohackers seek to better themselves or others by “hacking the brain” to improve reflexes, learn faster, or treat psychological disorders. The modern neurohacking movement has been around since the 1980s. However, herbal supplements have been used to increase brain function for hundreds of years. After a brief period marked by a lack of research in the area, neurohacking started regaining interest in the early 2000s. Currently, most neurohacking is performed via do-it-yourself (DIY) methods by in-home users.

<span class="mw-page-title-main">Intelligence amplification</span> Use of information technology to augment human intelligence

Intelligence amplification (IA) refers to the effective use of information technology in augmenting human intelligence. The idea was first proposed in the 1950s and 1960s by cybernetics and early computer pioneers.

Following is a list of topics related to life extension:

<span class="mw-page-title-main">Neurolaw</span>

Neurolaw is a field of interdisciplinary study that explores the effects of discoveries in neuroscience on legal rules and standards. Drawing from neuroscience, philosophy, social psychology, cognitive neuroscience, and criminology, neurolaw practitioners seek to address not only the descriptive and predictive issues of how neuroscience is and will be used in the legal system, but also the normative issues of how neuroscience should and should not be used.

Posthuman or post-human is a concept originating in the fields of science fiction, futurology, contemporary art, and philosophy that means a person or entity that exists in a state beyond being human. The concept aims at addressing a variety of questions, including ethics and justice, language and trans-species communication, social systems, and the intellectual aspirations of interdisciplinarity.

<i>N</i>-Phenylacetyl-<small>L</small>-prolylglycine ethyl ester Prodrug

N-Phenylacetyl-l-prolylglycine ethyl ester is promoted as a nootropic and is a prodrug of cyclic glycine-proline. Other names include the brand name Noopept, developmental code GVS-111, and proposed INN omberacetam.

<span class="mw-page-title-main">Selank</span> Chemical compound

Selank is a nootropic, anxiolytic peptide based drug developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). It is a synthetic analogue of human tuftsin.

Technoself studies, commonly referred to as TSS, is an emerging, interdisciplinary domain of scholarly research dealing with all aspects of human identity in a technological society focusing on the changing nature of relationships between the human and technology. As new and constantly changing experiences of human identity emerge due to constant technological change, technoself studies seeks to map and analyze these mutually influential developments with a focus on identity, rather than technical developments. Therefore, the self is a key concept of TSS. The term "technoself", advanced by Luppicini (2013), broadly denotes evolving human identity as a result of the adoption of new technology, while avoiding ideological or philosophical biases inherent in other related terms including cyborg, posthuman, transhuman, techno-human, beman, digital identity, avatar, and homotechnicus though Luppicini acknowledges that these categories "capture important aspects of human identity". Technoself is further elaborated and explored in Luppicini's "Handbook of Research on Technoself: Identity in a Technological Environment".

Neuroenhancement or cognitive enhancement is the experimental use of pharmacological or non-pharmacological methods intended to improve cognitive and affective abilities in healthy people who do not have a mental illness. Agents or methods of neuroenhancement are intended to affect cognitive, social, psychological, mood, or motor benefits beyond normal functioning.

The term directed evolution is used within the transhumanist community to refer to the idea of applying the principles of directed evolution and experimental evolution to the control of human evolution. In this sense, it is distinct from the use of the term in biochemistry, which refers only to the evolution of proteins and RNA. Maxwell J. Melhmanh has described directed evolution of humans as the Holy Grail of transhumanism. Oxford philosopher Julian Savulescu wrote that:

Humanity until this point has been a story of evolution for the survival genes - survival and reproduction ... we are entering a new phase of human evolution—evolution under reason—where human beings are masters of their destiny. Power has been transferred from nature to science.

Transhumanist politics constitutes a group of political ideologies that generally express the belief in improving human individuals through science and technology. Specific topics include space migration, and cryogenic suspension. It is considered the opposing ideal to the concept of bioconservatism, as Transhumanist politics argue for the use of all technology to enhance human individuals.

Bioconservatism is a philosophical and ethical stance that emphasizes caution and restraint in the use of biotechnologies, particularly those involving genetic manipulation and human enhancement. The term "bioconservatism" is a portmanteau of the words biology and conservatism.

References

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  41. 1 2 Michael Hauskeller, Better Humans?: Understanding the Enhancement Project, Acumen, 2013, ISBN   978-1-84465-557-1.
  42. 1 2 Allhoff, Fritz; Lin, Patrick (2011). "Ethics of Human Enhancement: An Executive Summary". Science and Engineering Ethics. 17 (2). Jesse Steinberg: 201–212. doi:10.1007/s11948-009-9191-9. PMID   20094921. S2CID   11143329.
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  45. 1 2 3 Coeckelbergh, Mark (June 2010). "Human development or human enhancement? A methodological reflection on capabilities and the evaluation of information technologies". Ethics and Information Technology. 13 (2): 81–92. doi: 10.1007/s10676-010-9231-9 .

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