Interstate 49 (I-49) is a north–south Interstate Highway that exists in multiple segments: the original portion entirely within the state of Louisiana with an additional signed portion extending from I-220 in Shreveport to the Arkansas state line, three newer sections in Arkansas, and a new section that opened in Missouri. Its southern terminus is in Lafayette, Louisiana, at I-10 while its northern terminus is in Kansas City, Missouri, at I-435 and I-470. Portions of the remaining roadway in Louisiana, Arkansas, and Texas, which will link Kansas City with New Orleans, are in various stages of planning or construction.
U.S. Route 412 is an east–west United States highway, first commissioned in 1982. U.S. 412 overlaps expressway-grade Cimarron Turnpike from Tulsa west to Interstate 35 and the Cherokee Turnpike from 5 miles (8.0 km) east of Chouteau, Oklahoma, to 8 miles (13 km) west of the Arkansas state line. It runs the entire length of the Oklahoma Panhandle and traverses the Missouri Bootheel.
U.S. Route 71 or U.S. Highway 71 is a major north–south United States highway that extends for over 1500 miles (2500 km) in the central United States. This original 1926 route has remained largely unchanged by encroaching Interstate highways. Currently, the highway's northern terminus is in International Falls, Minnesota at the Canada–US border, at the southern end of the Fort Frances-International Falls International Bridge to Fort Frances, Ontario. U.S. Route 53 also ends here. On the other side of the bridge, Trans-Canada Highway is an east–west route while Highway 71 is a north–south route. US 71's southern terminus is between Port Barre and Krotz Springs, Louisiana at an intersection with U.S. Route 190. For the entirety south of Kansas City, Missouri, US 71 runs parallel and concurrent with the existing and future Interstate 49. North of Kansas City, US 71 runs halfway between Interstate 29 and Interstate 35, which they split in the city at an interchange with Interstate 70.
U.S. Route 167 runs for 500 miles (800 km) from Ash Flat, Arkansas at U.S. Route 62/US Route 412 to Abbeville, Louisiana at Louisiana Highway 14. It goes through the cities of Little Rock, Arkansas, Alexandria, Louisiana, and Lafayette, Louisiana.
Route 13 is a highway in Missouri which runs almost the entire north–south length of the state. Its northern terminus is at U.S. Route 69/136 in Bethany. Its southern terminus is at the Arkansas state line in downtown Blue Eye, Missouri–Arkansas where it continues as Highway 21. It is one of the original state highways of Missouri.
Highway 16 is an east–west state highway in Arkansas. The route begins in Siloam Springs at US Highway 412 (US 412) and Highway 59 and runs east through Fayetteville and the Ozark National Forest to US Highway 67 Business (US 67B) in Searcy. Highway 16 was created during the 1926 Arkansas state highway numbering, and today serves as a narrow, winding, 2-lane road except for overlaps of 10 miles (16 km) through Fayetteville. Much of the highway winds through the Ozarks, including the Ozark National Forest, where a portion of the highway is designated as an Arkansas Scenic Byway. The route has two spur routes in Northwest Arkansas; in Fayetteville and Siloam Springs.
Highway 102 is an east–west state highway in Benton County, Arkansas. The highway connects two of western Benton County's population centers to Bentonville and Interstate 49 (I-49), the main north-south route in the Northwest Arkansas region.
Highway 180 is a state highway of 1.723 miles (2.773 km) in Fayetteville. The route begins at Interstate 49/US 62/US 71/Highway 16 and runs east through Fayetteville to School Avenue. Highway 180 is designated as part of the Trail of Tears National Historic Trail as well as Arkansas Heritage Trails System designations as the Butterfield Trail, Trail of Tears, and Civil War Trails.
Highway 265 is a designation for three state highways in Northwest Arkansas. The southern segment of 19.70 miles (31.70 km) runs from Highway 170 near Strickler north to I-49/US 71/Highway 112 in south Fayetteville. A second segment begins in east Fayetteville at Highway 16 and runs north through Springdale to Highway 94 in Rogers. Further north, a third segment of 3.324 miles (5.349 km) runs from Highway 94 in Pea Ridge north to the Missouri state line. The highways are maintained by the Arkansas Department of Transportation (ARDOT).
U.S. Route 60 has 25 current special routes. Of these, 20 are business routes, two alternate routes, one bypass route, and one truck route. US 60 has also had one additional business route, an additional bypass route, a temporary route, and another truck route.
Sixteen special routes of U.S. Route 62 currently exist. Seven of them lie within the state of Arkansas. Three existed in the past but have since been decommissioned.
Numerous special routes of U.S. Route 67, all business routes, exist. One other route, formerly an alternate route in western Illinois, has since been downgraded to state Route 267.
A total of eight special routes of U.S. Route 65 exist, divided between the U.S. states of Arkansas and Missouri. Currently, they are all business loops, although a spur route in Pine Bluff, Arkansas and bypass routes in Baton Rouge, Louisiana and Springfield, Missouri both existed in the past.
Six special routes of U.S. Route 412 exist.
Several special routes of U.S. Route 70 exist. In order from west to east, these special routes are as follows.
Twelve special routes of U.S. Route 63 currently exist. Arkansas and Missouri each contain five, with two in Iowa. There are also five former routings that have been removed from the system.
Several special routes of U.S. Route 15 exist. In order from south to north they are as follows.
Several special routes of U.S. Route 25 exist. In order from south to north they are as follows.
U.S. Highway 71 is a U.S. highway that runs from Krotz Springs, LA to the Fort Frances–International Falls International Bridge at the Canadian border. In Arkansas, the highway runs from the Louisiana state line near Doddridge to the Missouri state line near Bella Vista. In Texarkana, the highway runs along State Line Avenue with US 59 and partially runs in Texas. Other areas served by the highway include Fort Smith and Northwest Arkansas.
Interstate business routes are roads connecting a central or commercial district of a city or town with an Interstate bypass. These roads typically follow along local streets often along a former U.S. Route or state highway that had been replaced by an Interstate. Interstate business route reassurance markers are signed as either loops or spurs using a green shield shaped and numbered like the shield of the parent Interstate highway.
