U.S. Route 411 (US 411) is an alternate parallel-highway associated with US 11. It extends for about 309.7 miles (498.4 km) from US 78 in Leeds, Alabama, to US 25W/US 70 in Newport, Tennessee. US 411 travels through northeastern Alabama, northwestern Georgia, and southeastern Tennessee. It is signed north-south, as with most highways that have odd numbers, but the route runs primarily in a northeast-southwest direction, and covers a more east-west mileage than it does north-south. Notable towns and cities along its route include Gadsden, Alabama; Rome, Georgia; Cartersville, Georgia; Maryville, Tennessee; Sevierville, Tennessee, and Newport, Tennessee.
U.S. Route 11E (US 11E) is a divided highway of US 11 in the U.S. states of Tennessee and Virginia. The United States Numbered Highway, which is complemented by US 11W to the north and west, runs 120.94 miles (194.63 km) from US 11, US 11W, and US 70 in Knoxville, Tennessee, north and east to US 11, US 11W, US 19, and US 421 in Bristol, Virginia. US 11E connects Knoxville and the twin cities of Bristol, Virginia, and Bristol, Tennessee, with the East Tennessee communities of Morristown, Greeneville, and Johnson City. The U.S. Highway runs concurrently with US 70 and US 25W east of Knoxville, US 321 from Greeneville and Johnson City, and both US 19W and US 19 between Johnson City and Bristol. US 11E also has an unsigned concurrency with State Route 34 (SR 34) for almost all of its course in Tennessee.
State Route 2 is a 197-mile-long (317 km) west–to–east state highway in the U.S. state of Tennessee. It begins in Murfreesboro, in Rutherford County, and ends near Farragut in Loudon County. The route is both a primary and secondary route. Most of the route is unsigned.
U.S. Route 25W is the western branch of U.S. Route 25 from Newport, Tennessee, where US 25 splits into US 25E and US 25W, to North Corbin, Kentucky, where the two highways rejoin.
State Route 58, also locally called "Highway 58", is a north–south state highway in the U.S. state of Tennessee that serves as a major route for many communities in Roane, Meigs, and Hamilton counties.
State Route 66 is a state-maintained highway in eastern Tennessee, including a six-lane divided highway known as Winfield Dunn Parkway in Sevier County, a four-lane expressway in Hamblen and Jefferson counties and a two-lane rural collector through mountainous terrain continuing to the northeast terminus in Hancock County.
State Route 9 (SR 9) is a west-to-east state highway in the U.S. state of Tennessee that is 131.33 miles (211.36 km) long. It begins in Campbell County and ends in Cocke County. SR 9 is little-known by the general public by this designation as it is overlain by U.S. Route 25W and U.S. Route 25 east of Newport; the "9" designation is seen on mileposts. The entire route is located in East Tennessee. Despite running concurrent with a North-South US Route, Route 9 is signed as east-west.
State Route 62 is a 87.5-mile-long (140.8 km) west-to-east highway in the U.S. state of Tennessee. It is designated as a primary route except for the short segment between SR 169 and its eastern terminus, which is secondary.
State Route 131 is a south-to-north highway in the U.S. state of Tennessee that is 68.8-mile (110.7 km) long. It is designated as a secondary route.
State Route 96 is an east–west and north–south highway in Middle Tennessee. The road begins in Dickson and ends in Granville. The current length is 126.7 mi (203.9 km). Along its path it goes through 10 counties. Locals mostly refer to it as Highway 96.
State Route 71 is a north–south state highway in Tennessee. For most of the length it is a "hidden" route, as it coincides with US 441 in all but a short section in Knoxville. The road begins at the North Carolina state line in Sevier County within the Great Smoky Mountains National Park at Newfound Gap and ends at an intersection with US 25W, SR 116, and SR 9 (hidden) in Rocky Top. Along its length SR 71 passes through Sevier County, a small portion of Blount County, Knox County, Anderson County, and in and out of Campbell County. Despite being signed on Hall of Fame Parkway in Knoxville, Tennessee, the Knox County TDOT map ignores SR 71 while SR 33 has a concurrency with US 441.
State Route 10 is a south–north route from the Alabama state line in Lincoln County to the Kentucky state line in Macon County.
State Route 13, in the United States, is a south–north route from the Alabama border in Wayne County to the Kentucky border in Montgomery County. The entire route is located in western Middle Tennessee.
State Route 15 is a west–east route from Memphis to Monteagle. For much of its route it has an unsigned concurrency with U.S. Route 64. SR 15 does travel through the southern part of all 3 Grand Divisions of the state: West Tennessee, Middle Tennessee, and East Tennessee.
State Route 76 (SR 76) is a state highway in Tennessee, traversing the state in a northeast-southwest axis from east of Memphis to north of Nashville. SR 76 is unique in that it actually changes its cardinal directions in Clarksville at the junction with US 41A and US 41A Bypass.
U.S. Route 441 stretches for 83.28 miles (134.03 km) through the mountains of East Tennessee, connecting Rocky Top with Knoxville, Sevierville, Gatlinburg, and the Great Smoky Mountains National Park, crossing into North Carolina at Newfound Gap. Near its northern terminus, US 441 crosses over Norris Dam and passes through Norris Dam State Park.
U.S. Route 129 is a north–south United States highway that runs for 52.8 miles (85.0 km) in East Tennessee, from the North Carolina state line, near Tapoco, to Knoxville. In Tennessee, the highway is completely overlapped by unsigned State Route 115. In the Greater Knoxville area, US 129 serves as a six-lane controlled-access highway known as Alcoa Highway.
State Route 32 is a state highway in East Tennessee. For most of its route, it is an unsigned companion route concurrent with U.S. Route 25E. The highway stretches 89 miles from the North Carolina state line to the Tennessee-Kentucky state line near the town of Cumberland Gap.
State Route 72 is a 43.3-mile-long (69.7 km) state highway in the eastern portion of U.S. state of Tennessee. It travels through the towns of Vonore and Loudon.
State Route 28 is a state highway in the state of Tennessee, traversing the state in a north–south axis from south of Jasper to the Kentucky state line at Static.
US 411 / SR 61 at Georgia state line in Tennga, Georgia 
SR 696 (to 
SR 600) at Virginia state line in Hancock County
